Posiciones Liga BetPlay 2021-1
| Pos | Club | J | G | E | P | GF | GC | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Atlético Nacional | 18 | 10 | 4 | 4 | 37 | 15 | 22 | 34 |
| 2 |  Independiente Santa Fé | 18 | 9 | 6 | 3 | 25 | 14 | 11 | 33 |
| 3 |  Millonarios F.C. | 18 | 10 | 3 | 5 | 25 | 18 | 7 | 33 |
| 4 |  Deportivo Cali | 18 | 8 | 7 | 3 | 19 | 14 | 5 | 31 |
| 5 |  Deportes Tolima | 18 | 8 | 6 | 4 | 22 | 14 | 8 | 30 |
| 6 |  Equidad C.D. | 18 | 8 | 6 | 4 | 21 | 18 | 3 | 30 |
| 7 |  Atlético Junior | 18 | 8 | 5 | 5 | 21 | 13 | 8 | 29 |
| 8 |  América de Cali | 18 | 7 | 8 | 3 | 19 | 12 | 7 | 29 |
| 9 |  Independiente Medellín | 18 | 6 | 8 | 4 | 17 | 15 | 2 | 26 |
| 10 |  Jaguares F.C. | 18 | 7 | 4 | 7 | 21 | 21 | 0 | 25 |
| 11 |  Atlético Bucaramanga | 18 | 6 | 6 | 6 | 20 | 16 | 4 | 24 |
| 12 |  Deportivo Pasto | 18 | 4 | 11 | 3 | 19 | 20 | -1 | 23 |
| 13 |  Boyacá Chico | 18 | 5 | 4 | 9 | 17 | 20 | -3 | 19 |
| 14 |  Deportivo Pereira | 18 | 4 | 6 | 8 | 16 | 24 | -8 | 18 |
| 15 |  Once Caldas | 18 | 3 | 8 | 7 | 20 | 23 | -7 | 17 |
| 16 |  Envigado F.C. | 18 | 3 | 8 | 7 | 15 | 23 | -8 | 17 |
| 17 |  Patriotas | 18 | 5 | 2 | 11 | 17 | 31 | -14 | 17 |
| 18 |  Aguilas Doradas | 18 | 2 | 8 | 8 | 13 | 24 | -11 | 14 |
| 19 |  Alianza Petrolera | 18 | 0 | 6 | 12 | 10 | 39 | -29 | 6 |
